Ppp3cb^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ppp3cb^M4Btlr
• Name: protein phosphatase 3, catalytic subunit, beta isoform; mutation 4, Bruce Beutler
• MGI ID: MGI:6113605
• Synonyms: Redwood
• Gene: Ppp3cb Location: Chr14:20549432-20596641 bp, - strand Genetic Position: Chr14, 11.53 cM, cytoband B
• Alliance: Ppp3cb^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 20,509,440 (v38) on chromosome 14, or base pair 37,134 in the GenBank genomic region NC_000080. The mutation corresponds to residue 1,380 in the mRNA sequence NM_008914 within exon 11 of 14 total exons. The mutation results in a methionine (M) to lysine (K) substitution at position 416 (M416K) in the encoded protein. (J:254905)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp3cb Mutation: 67 strains or lines available

References

• Original: J:254905 Zhong X, et al., Mutagenetix entry for Redwood. MGI Direct Data Submission. 2018
• All: 1 reference(s)