Muc2^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Muc2^m3Btlr
• Name: mucin 2; mutation 3, Bruce Beutler
• MGI ID: MGI:6113610
• Synonyms: nomoco
• Gene: Muc2 Location: Chr7:141276583-141308428 bp, + strand Genetic Position: Chr7, 87.1 cM, cytoband F5
• Alliance: Muc2^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 141,753,719 (v38) on chromosome 7, or base pair 63,380 in the GenBank genomic region NC_000073. The mutation corresponds to residue 6,852 in the mRNA sequence NM_023566 within exon 14 of 16 total exons. The mutation results in a cysteine to arginine substitution at position 365 (C365R) in the protein. (J:254906)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Muc2 Mutation: 84 strains or lines available

References

• Original: J:254906 McAlpine W, et al., Mutagenetix entry for nomoco. MGI Direct Data Submission. 2018
• All: 1 reference(s)