Ticam2^M3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ticam2^M3Btlr
• Name: TIR domain containing adaptor molecule 2; mutation 3, Bruce Beutler
• MGI ID: MGI:6113633
• Synonyms: Messi
• Gene: Ticam2 Location: Chr18:46691298-46707600 bp, - strand Genetic Position: Chr18, 24.65 cM
• Alliance: Ticam2^M3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 46,560,922 (v38) on chromosome 18, or base pair 13,612 in the GenBank genomic region NC_000084. The mutation corresponds to residue 573 in the mRNA sequence NM_173394 within exon 3 of 3 total exons. The mutation results in substitution of lysine (K) 33 to a premature stop codon (K33*) in the protein. (J:254912)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ticam2 Mutation: 25 strains or lines available

References

• Original: J:254912 Ochoa CD, et al., Mutagenetix entry for Messi. MGI Direct Data Submission. 2018
• All: 1 reference(s)