Tap2^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tap2^m3Btlr
• Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); mutation 3, Bruce Beutler
• MGI ID: MGI:6113680
• Synonyms: date2
• Gene: Tap2 Location: Chr17:34423453-34435295 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Tap2^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 34,214,032 (v38) on chromosome 17, or base pair 9,554 in the GenBank genomic region NC_000083. The mutation corresponds to residue 1,440 in the mRNA sequence NM_011530 within exon 8 of 12 total exons. The mutation results in substitution of tyrosine 429 for a premature stop codon (Y429*) in the protein. (J:254929)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tap2 Mutation: 28 strains or lines available

References

• Original: J:254929 Zeng M, et al., Mutagenetix entry for date2. MGI Direct Data Submission. 2018
• All: 1 reference(s)