Tg(Fn1-cre)41Stl
Transgene Detail

Summary

• Symbol: Tg(Fn1-cre)41Stl
• Name: transgene insertion 41, Susumu Tonegawa
• MGI ID: MGI:6113839
• Synonyms: Tg(FN1-Cre)41
• Transgene: Tg(Fn1-cre)41Stl Location: unknown
• Alliance: Tg(Fn1-cre)41Stl page

Transgene origin

• Strain of Origin: C57BL/6JCrlj

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Fn1-cre)41Stl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fn1 (MGI:95566)

• Mutation details: The cre recombinase sequence and the FRTs flanked kanamycin resistance gene was inserted by BAC recombineering methods in-frame following the first exon of mouse FN1 gene in a BAC clone RP24-211L16 containing the whole FN1. Resistant clones were selected and confirmed for appropriate homologous recombination, after which kanamycin was removed using the site-specific recombinase FLP. The final vector was microinjected into pronuclei of fertilized C57BL/6JCrlj eggs. Founder information is not available. Line 41 transgenic line was established and maintained in the same background. (J:252495)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fn1 (mouse) Summary of all recombinase alleles driven by Fn1. Alliance mouse Fn1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:252495 Roy DS, et al., Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories. Cell. 2017 Aug 24;170(5):1000-1012.e19
• All: 1 reference(s)