Blk^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Blk^m1Btlr
• Name: B lymphoid kinase; mutation 1, Bruce Beutler
• MGI ID: MGI:6113863
• Synonyms: blaenka
• Gene: Blk Location: Chr14:63610285-63654486 bp, - strand Genetic Position: Chr14, 33.25 cM
• Alliance: Blk^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 63,384,002 (v38) on chromosome 14, or base pair 33,186 in the GenBank genomic region NC_000080. The mutation corresponds to residue 697 in the NM_007549 mRNA sequence in exon 5 of 13 total exons. The mutation results in a serine (S) to proline (P) substitution at position 93 (S93P) in the protein. (J:255004)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Blk Mutation: 28 strains or lines available

References

• Original: J:255004 Yue T, et al., Mutagenetix entry for blaenka. MGI Direct Data Submission. 2018
• All: 1 reference(s)