Cd8b1^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd8b1^M1Btlr
• Name: CD8 subunit beta 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6113877
• Synonyms: Carlsbad
• Gene: Cd8b1 Location: Chr6:71299772-71314476 bp, + strand Genetic Position: Chr6, 32.14 cM
• Alliance: Cd8b1^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 71,334,101 (v38) on chromosome 6, or base pair 11,290 in the GenBank genomic region NC_000072. The mutation corresponds to residue 649 in the mRNA sequence NM_009858 within exon 5 of 6 total exons. The mutation results in an arginine (R) to glycine (G) substitution at position 202 (R202G) in the protein. (J:255009)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd8b1 Mutation: 20 strains or lines available

References

• Original: J:255009 Zeng M, et al., Mutagenetix entry for Carlsbad. MGI Direct Data Submission. 2018
• All: 1 reference(s)