Dsg4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dsg4^m1Btlr
• Name: desmoglein 4; mutation 1, Bruce Beutler
• MGI ID: MGI:6114027
• Synonyms: burrito
• Gene: Dsg4 Location: Chr18:20569232-20604878 bp, + strand Genetic Position: Chr18, 11.35 cM
• Alliance: Dsg4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 20,451,862 (v38) on chromosome 18, or base pair 15,688 in the GenBank genomic region NC_000084 for the gene. The mutation corresponds to residue 766 in the NM_181564 mRNA sequence in exon 6 of 16 total exons. The mutation results in a valine (V) to glutamic acid (E) substitution at position 211 (V211E) in the protein. (J:255183)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dsg4 Mutation: 86 strains or lines available

References

• Original: J:255183 Prince L, et al., Mutagenetix entry for burrito. MGI Direct Data Submission. 2018
• All: 1 reference(s)