Ighd^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ighd^M1Btlr
• Name: immunoglobulin heavy constant delta; mutation 1, Bruce Beutler
• MGI ID: MGI:6114049
• Synonyms: Surface
• Gene: Ighd Location: Chr12:113371155-113379944 bp, - strand Genetic Position: Chr12, 62.1 cM
• Alliance: Ighd^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 113,416,199 (v38) on chromosome 12, or base pair 126 in the GenBank genomic region NC_000078. The mutation corresponds to residue 126 in the cDNA sequence ENSMUST00000194162.5 within exon 1 of 5 total exons. The mutation results in a lysine (K) to glutamic acid (E) substitution at position 42 (K42E) in the protein. (J:255202)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ighd Mutation: 19 strains or lines available

References

• Original: J:255202 Zeng M, et al., Mutagenetix entry for Surface. MGI Direct Data Submission. 2018
• All: 1 reference(s)