Ighd^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ighd^m2Btlr
• Name: immunoglobulin heavy constant delta; mutation 2, Bruce Beutler
• MGI ID: MGI:6114054
• Synonyms: surface2
• Gene: Ighd Location: Chr12:113371155-113379944 bp, - strand Genetic Position: Chr12, 62.1 cM
• Alliance: Ighd^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 113,416,041 (v38) on chromosome 12, or base pair 284 in the GenBank genomic region NC_000078. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in skipping of the 282-nucleotide exon 1 (out of 5 total exons). The next available start codon is in exon 2. (J:255203)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ighd Mutation: 19 strains or lines available

References

• Original: J:255203 Zeng M, et al., Mutagenetix entry for surface2. MGI Direct Data Submission. 2018
• All: 1 reference(s)