Prkcq^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkcq^m1Btlr
• Name: protein kinase C, theta; mutation1, Bruce Beutler
• MGI ID: MGI:6114110
• Synonyms: celina
• Gene: Prkcq Location: Chr2:11176922-11306033 bp, + strand Genetic Position: Chr2, 8.42 cM
• Alliance: Prkcq^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 11,283,849 (v38) on chromosome 2, or base pair 111,946 in the GenBank genomic region NC_000068. The mutation corresponds to residue 1,700 in the mRNA sequence NM_008859 within exon 15 of 18 total exons. The mutation results in a threonine (T) to alanine (A) substitution at position 538 (T538A) in the protein. (J:255214)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcq Mutation: 51 strains or lines available

References

• Original: J:255214 Choi JH, et al., Mutagenetix entry for celina. MGI Direct Data Submission. 2018
• All: 1 reference(s)