Prkdc^m6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkdc^m6Btlr
• Name: protein kinase, DNA activated, catalytic polypeptide; mutation 6, Bruce Beutler
• MGI ID: MGI:6114136
• Synonyms: screamer5
• Gene: Prkdc Location: Chr16:15455730-15660099 bp, + strand Genetic Position: Chr16, 10.09 cM, cytoband B1
• Alliance: Prkdc^m6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 15,687,404 (v38) on chromosome 16, or base pair 49,962 in the GenBank genomic region NC_000082. The mutation corresponds to residue 2,592 in the mRNA sequence NM_011159 within exon 23 of 86 total exons. The mutation results in an isoleucine (I) to leucine (L) substitution at position 857 (I857L) in the protein. (J:255221)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkdc Mutation: 417 strains or lines available

References

• Original: J:255221 Yue T, et al., Mutagenetix entry for screamer5. MGI Direct Data Submission. 2018
• All: 1 reference(s)