Prkdc^M9Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkdc^M9Btlr
• Name: protein kinase, DNA activated, catalytic polypeptide; mutation 9, Bruce Beutler
• MGI ID: MGI:6114639
• Synonyms: Screamer8
• Gene: Prkdc Location: Chr16:15455730-15660099 bp, + strand Genetic Position: Chr16, 10.09 cM, cytoband B1
• Alliance: Prkdc^M9Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 15,719,433 (v38) on chromosome 16, or base pair 81,991 in the GenBank genomic region NC_000082. The mutation corresponds to residue 5,170 in the mRNA sequence NM_011159 within exon 39 of 86 total exons. The mutation results in a valine (V) to alanine (A) substitution at position 1716 (V1716A) in the protein. (J:255268)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkdc Mutation: 418 strains or lines available

References

• Original: J:255268 Yue T, et al., Mutagenetix entry for Screamer8. MGI Direct Data Submission. 2018
• All: 1 reference(s)