Rac2^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rac2^M4Btlr
• Name: Rac family small GTPase 2; mutation 4, Bruce Beutler
• MGI ID: MGI:6114684
• Synonyms: Potter2
• Gene: Rac2 Location: Chr15:78443369-78456983 bp, - strand Genetic Position: Chr15, 37.57 cM
• Alliance: Rac2^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 78,565,454 (v38) on chromosome 15, or base pair 7,330 in the GenBank genomic region NC_000081 encoding the gene. The mutation corresponds to residue 413 in the mRNA sequence NM_009008 within exon 4 of 7 total exons. The mutation results in an asparagine to serine substitution at position 92 (N92S) in the protein. (J:255273)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rac2 Mutation: 17 strains or lines available

References

• Original: J:255273 Choi JH, et al., Mutagenetix entry for Potter2. MGI Direct Data Submission. 2018
• All: 1 reference(s)