Rims4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rims4^m1Btlr
• Name: regulating synaptic membrane exocytosis 4; mutation 1, Bruce Beutler
• MGI ID: MGI:6114721
• Synonyms: demure
• Gene: Rims4 Location: Chr2:163701671-163760603 bp, - strand Genetic Position: Chr2, 84.52 cM
• Alliance: Rims4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 163,864,120 (v38) on chromosome 2, or base pair 54,871 in the GenBank genomic region NC_000068. The mutation corresponds to residue 593 in the NM_1832023 mRNA sequence in exon 6 of 6 total exons. The mutation results in a valine (V) to glutamic acid (E) substitution at position 198 (V198E) in the protein. (J:255287)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rims4 Mutation: 37 strains or lines available

References

• Original: J:255287 SoRelle J, et al., Mutagenetix entry for demure. MGI Direct Data Submission. 2018
• All: 1 reference(s)