Vangl1^tm1Jdax
Targeted Allele Detail

Summary

• Symbol: Vangl1^tm1Jdax
• Name: VANGL planar cell polarity 1; targeted mutation 1, Jeffrey Axelrod
• MGI ID: MGI:6115036
• Synonyms: Vangl1CKO
• Gene: Vangl1 Location: Chr3:102060899-102112009 bp, - strand Genetic Position: Chr3, 44.3 cM
• Alliance: Vangl1^tm1Jdax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199740
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin selection cassette and a 3' loxP site are inserted downstream of exon 4 and another loxP site is inserted upstream of exon 4. (J:199740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vangl1 Mutation: 85 strains or lines available

References

• Original: J:199740 Vladar EK, et al., Microtubules enable the planar cell polarity of airway cilia. Curr Biol. 2012 Dec 4;22(23):2203-12
• All: 3 reference(s)