Sfrp4^tm1Maki
Targeted Allele Detail

Summary

• Symbol: Sfrp4^tm1Maki
• Name: secreted frizzled-related protein 4; targeted mutation 1, Masashi Kitazawa
• MGI ID: MGI:6115786
• Synonyms: sFRP4^LacZ
• Gene: Sfrp4 Location: Chr13:19807345-19816995 bp, + strand Genetic Position: Chr13, 6.99 cM
• Alliance: Sfrp4^tm1Maki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256184
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced by a nlacZ-neo selection cassette. (J:256184)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp4 Mutation: 18 strains or lines available

References

• Original: J:256184 Haraguchi R, et al., sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss. Sci Rep. 2016 Apr 27;6:25198
• All: 1 reference(s)