Fth1^tm1.1Ruvi
Targeted Allele Detail

Summary

• Symbol: Fth1^tm1.1Ruvi
• Name: ferritin heavy polypeptide 1; targeted mutation 1.1, Ruben Vidal
• MGI ID: MGI:6115889
• Gene: Fth1 Location: Chr19:9957962-9962462 bp, + strand Genetic Position: Chr19, 6.23 cM, cytoband A-C
• Alliance: Fth1^tm1.1Ruvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244236
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted upstream of exon 1 and a loxP site was inserted downstream of exon 4 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 1 through 4. (J:244236)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fth1 Mutation: 14 strains or lines available

References

• Original: J:244236 Li W, et al., Systemic and cerebral iron homeostasis in ferritin knock-out mice. PLoS One. 2015;10(1):e0117435
• All: 1 reference(s)