Reep1^{Gt(OST398247)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Reep1^{Gt(OST398247)Tigm}
• Name: receptor accessory protein 1; gene trap OST398247, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:6116844
• Gene: Reep1 Location: Chr6:71684545-71787694 bp, + strand Genetic Position: Chr6, 32.2 cM
• Alliance: Reep1^{Gt(OST398247)Tigm} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239250
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted downstream of exon 1. Immunoblotting of multiple tissues confirmed absence of protein. (J:239250)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reep1 Mutation: 16 strains or lines available

References

• Original: J:239250 Renvoise B, et al., Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation. Hum Mol Genet. 2016 Dec 1;25(23):5111-5125
• All: 2 reference(s)