Haus6^tm1.2Sdwb
Targeted Allele Detail

Summary

• Symbol: Haus6^tm1.2Sdwb
• Name: HAUS augmin-like complex, subunit 6; targeted mutation 1.2, Sadanori Watanabe
• MGI ID: MGI:6117369
• Gene: Haus6 Location: Chr4:86497092-86530292 bp, - strand Genetic Position: Chr4, 40.69 cM
• Alliance: Haus6^tm1.2Sdwb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235084
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the selection cassette and exon 1. (J:235084)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Haus6 Mutation: 38 strains or lines available

References

• Original: J:235084 Watanabe S, et al., Intra-spindle Microtubule Assembly Regulates Clustering of Microtubule-Organizing Centers during Early Mouse Development. Cell Rep. 2016 Apr 5;15(1):54-60
• All: 1 reference(s)