Cept1^tm1.1Sem
Targeted Allele Detail

Summary

• Symbol: Cept1^tm1.1Sem
• Name: choline/ethanolaminephosphotransferase 1; targeted mutation 1.1, Clay F Semenkovich
• MGI ID: MGI:6117770
• Synonyms: Cept1 lox
• Gene: Cept1 Location: Chr3:106409576-106455118 bp, - strand Genetic Position: Chr3, 46.49 cM
• Alliance: Cept1^tm1.1Sem page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:249456
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked by loxP sites and an FRT site flanked neomycin resistance gene cassette was inserted into intron 2. The neo cassette was removed via subsequent Flp-mediated recombination. (J:249456)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cept1 Mutation: 23 strains or lines available

References

• Original: J:249456 Funai K, et al., Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function. Diabetes. 2016 Feb;65(2):358-70
• All: 1 reference(s)