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Cept1tm1.1Sem
Targeted Allele Detail
Summary
Symbol: Cept1tm1.1Sem
Name: choline/ethanolaminephosphotransferase 1; targeted mutation 1.1, Clay F Semenkovich
MGI ID: MGI:6117770
Synonyms: Cept1 lox
Gene: Cept1  Location: Chr3:106409576-106455118 bp, - strand  Genetic Position: Chr3, 46.49 cM
Alliance: Cept1tm1.1Sem page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:249456
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 3 was flanked by loxP sites and an FRT site flanked neomycin resistance gene cassette was inserted into intron 2. The neo cassette was removed via subsequent Flp-mediated recombination. (J:249456)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cept1 Mutation:  23 strains or lines available
References
Original:  J:249456 Funai K, et al., Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function. Diabetes. 2016 Feb;65(2):358-70
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory