Ccdc134^tm1.2Jhua
Targeted Allele Detail

Summary

• Symbol: Ccdc134^tm1.2Jhua
• Name: coiled-coil domain containing 134; targeted mutation 1.2, Jing Huang
• MGI ID: MGI:6117856
• Synonyms: Ccdc134^-
• Gene: Ccdc134 Location: Chr15:82012123-82026404 bp, + strand Genetic Position: Chr15, 38.47 cM
• Alliance: Ccdc134^tm1.2Jhua page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256995
• Parent Cell Line: B6/BLU (ES Cell)
• Strain of Origin: C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 2 and an FRT flanked neo cassette and loxP site were inserted in intron 6 via homologous recombination. Recombinase-mediated recombination removed exons 3-6 and the neo cassette. (J:256995)

Expression

In Mice Carrying this Mutation:	25 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc134 Mutation: 20 strains or lines available

References

• Original: J:256995 Yu B, et al., CCDC134 serves a crucial role in embryonic development. Int J Mol Med. 2018 Jan;41(1):381-390
• All: 1 reference(s)