Tg(Grpr-icre)#Mlag
Transgene Detail

Summary

• Symbol: Tg(Grpr-icre)#Mlag
• Name: transgene insertion, Malin C Lagerstrom
• MGI ID: MGI:6119666
• Synonyms: Grpr-Cre
• Transgene: Tg(Grpr-icre)#Mlag Location: unknown
• Alliance: Tg(Grpr-icre)#Mlag page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Grpr-icre)#Mlag expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Grpr (MGI:95836)

• Mutation details: The transgene was created by modifying BAC clone RP23-395E7 by inserting an improved cre recombinase gene (icre) to replace exon 1 of mouse Grpr gene. An FRT-flanked ampicillin resistance cassette was removed prior to injection. Two lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:247582)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grpr (mouse) Summary of all recombinase alleles driven by Grpr. Comparative matrix view of recombinase activities Alliance mouse Grpr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:247582 Aresh B, et al., Spinal cord interneurons expressing the gastrin-releasing peptide receptor convey itch through VGLUT2-mediated signaling. Pain. 2017 May;158(5):945-961
• All: 4 reference(s)