Tg(H2-D^d)28Bee
Transgene Detail

Summary

• Symbol: Tg(H2-D^d)28Bee
• Name: transgene insertion 28 Friedrich Beermann
• MGI ID: MGI:6120900
• Synonyms: Floxed H-2D^d, loxD^d Tg
• Transgene: Tg(H2-D^d)28Bee Location: unknown
• Alliance: Tg(H2-D^d)28Bee page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-D^d)28Bee expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	H2-D (MGI:1933561)

• Mutation details: An H2-D gene was flanked by loxP sites at the promoter region and the exons that encode the alpha1 and alpha2 domains. This line expressed H-2D at levels similar (80%) to B10.D2 (H-2) mice. Upon cre-mediated recombination, expression of H2-D is abolished. (J:72831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:72831 Ioannidis V, et al., Cre Recombinase-Mediated Inactivation of H-2D(d) Transgene Expression: Evidence for Partial Missing Self-Recognition by Ly49A NK Cells. J Immunol. 2001 Dec 1;167(11):6256-62
• All: 3 reference(s)