Rpl22l1^tm1.1Psam
Targeted Allele Detail

Summary

• Symbol: Rpl22l1^tm1.1Psam
• Name: ribosomal protein L22 like 1; targeted mutation 1.1, Paul S Amieux
• MGI ID: MGI:6121072
• Gene: Rpl22l1 Location: Chr3:28859660-28861573 bp, + strand Genetic Position: Chr3, 12.27 cM
• Alliance: Rpl22l1^tm1.1Psam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251438
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of the second coding exon. An additional loxP site was inserted downstream of the third coding exon. Cre-mediated recombination removed the sequence encompassing the second and third coding exons. (J:251438)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpl22l1 Mutation: 14 strains or lines available

References

• Original: J:251438 Zhang Y, et al., Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017 Jan 10;18(2):545-556
• All: 1 reference(s)