Gtsf1l^em1Miya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gtsf1l^em1Miya
• Name: gametocyte specific factor 1-like; endonuclease-mediated mutation 1, Jun-ichi Miyazaki
• MGI ID: MGI:6121438
• Gene: Gtsf1l Location: Chr2:162928954-162929775 bp, - strand Genetic Position: Chr2, 84.04 cM, cytoband H3
• Alliance: Gtsf1l^em1Miya page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: A frameshift mutation was created by the insertion of coding sequence suspected to derive from Thg1l and Gm2420. RT-PCR and western blot analyses confirmed the absence of expression in testes from homozygous mice at 8 weeks of age. (J:251285)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gtsf1l Mutation: 9 strains or lines available

References

• Original: J:251285 Takemoto N, et al., Gtsf1l and Gtsf2 Are Specifically Expressed in Gonocytes and Spermatids but Are Not Essential for Spermatogenesis. PLoS One. 2016;11(3):e0150390
• All: 1 reference(s)