Shld1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shld1^em1(IMPC)Mbp
• Name: shieldin complex subunit 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6140112
• Gene: Shld1 Location: Chr2:132528871-132592975 bp, + strand Genetic Position: Chr2, 64.74 cM, cytoband F3
• Alliance: Shld1^em1(IMPC)Mbp page
• IMPC: Shld1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: This allele from IMPC was generated at UC Davis by injecting CAS9 Protein and 2 guide sequences GCATCCCAGAGAGTCAGCCAGGG, CCAGCAGCCTGTCAGGAGAGAGC, which resulted in a Intra-exdel deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Shld1 Mutation: 78 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)