Prss53^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss53^{em1(IMPC)Wtsi}
• Name: serine protease 53; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6140219
• Gene: Prss53 Location: Chr7:127485013-127490142 bp, - strand Genetic Position: Chr7, 69.81 cM
• Alliance: Prss53^{em1(IMPC)Wtsi} page
• IMPC: Prss53 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Welcome Trust Sanger Institute by injecting CAS9 RNA and 4 guide sequences GTTCTCGCTTGGCCACATCTAGG, CCAGTCCTGATACCCGTTCTCAT, CGTAACTGCCTGGCCCAGGTTGG, GGCGGAAAAGCAGCTTTTATTGG, which resulted in a Exon Deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prss53 Mutation: 20 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)