Kcnj6^em1.1Ktaka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnj6^em1.1Ktaka
• Name: potassium inwardly-rectifying channel, subfamily J, member 6; endonuclease-mediated mutation 1.1, Kazuo Takahama
• MGI ID: MGI:6144032
• Synonyms: Girk2^floxed
• Gene: Kcnj6 Location: Chr16:94549495-94798560 bp, - strand Genetic Position: Chr16, 55.44 cM
• Alliance: Kcnj6^em1.1Ktaka page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology inserted loxP sites flanking exon 4a and a FRT-flanked neomycin selection cassette downstream of the floxed exon. Flp-mediated recombination deleted the neomycin cassette. (J:257982)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnj6 Mutation: 26 strains or lines available

Notes

ES Cells: 6NK7

References

• Original: J:257982 Honda I, et al., Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice. Neurosci Lett. 2018 Feb 5;665:140-146
• All: 1 reference(s)