Canx^tm1.2Osb
Targeted Allele Detail

Summary

• Symbol: Canx^tm1.2Osb
• Name: calnexin; targeted mutation 1.2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6144081
• Synonyms: Canx^fl, tm1b
• Gene: Canx Location: Chr11:50184788-50216500 bp, - strand Genetic Position: Chr11, 30.46 cM
• Alliance: Canx^tm1.2Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250114
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 were flanked by loxP sites. An frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. (J:250114)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Canx Mutation: 55 strains or lines available

References

• Original: J:250114 Tokuhiro K, et al., Calreticulin is required for development of the cumulus oocyte complex and female fertility. Sci Rep. 2015 Sep 21;5:14254
• All: 2 reference(s)