Slc22a17^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc22a17^em1(IMPC)H
• Name: solute carrier family 22 (organic cation transporter), member 17; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6144258
• Gene: Slc22a17 Location: Chr14:55143761-55150589 bp, - strand Genetic Position: Chr14, 27.99 cM
• Alliance: Slc22a17^em1(IMPC)H page
• IMPC: Slc22a17 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences GATGTATGAGGGTAAGATGCAGG, TACTTCAAAGCTGATGTATGAGG, CCCTGCCTAGACCCTTTAAAAGG, CAGCTGAAATCTGGGACCTAGGG, which resulted in a 400-bp exon deletion, including a critical exon to generate a knock-out. (J:237616)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Slc22a17 Mutation: 23 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)