C4b^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: C4b^em1(IMPC)H
• Name: complement C4B (Chido blood group); endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6144264
• Gene: C4b Location: Chr17:34947354-34962856 bp, - strand Genetic Position: Chr17, 18.29 cM
• Alliance: C4b^em1(IMPC)H page
• IMPC: C4b gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences CCAATACAGAGCCTAAGGTAGGG, CCCAATACAGAGCCTAAGGTAGG, CCCTAGGGTGGCTCTATCTGTGG, GTGGAGTTGCCTTACATAGAAGG, which resulted in a Exon Deletion. (J:237616)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any C4b Mutation: 105 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)