Polrmt^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Polrmt^tm1.1Arte
• Name: polymerase (RNA) mitochondrial (DNA directed); targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6147647
• Synonyms: Polrmt^loxP
• Gene: Polrmt Location: Chr10:79571957-79582415 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Polrmt^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217486
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and F3 flanked puro cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp-mediated recombination removed the puro cassette. (J:217486, J:258184)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Polrmt Mutation: 45 strains or lines available

References

• Original: J:217486 Kuhl I, et al., POLRMT does not transcribe nuclear genes. Nature. 2014 Oct 9;514(7521):E7-11
• All: 3 reference(s)