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Pgap6tm1Osb
Targeted Allele Detail
Summary
Symbol: Pgap6tm1Osb
Name: post-glycosylphosphatidylinositol attachment to proteins 6; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:6147693
Synonyms: Pgap6-, Pgap6tm1Maik
Gene: Pgap6  Location: Chr17:26332290-26342228 bp, + strand  Genetic Position: Chr17, 13.06 cM, cytoband B1
Alliance: Pgap6tm1Osb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:258200
Parent Cell Line:  EGR-G101 (ES Cell)
Strain of Origin:  C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    An exon-trap construct from EUCOMM was used to disrupt the gene. (J:258200)
Generation of the Pgap6tm1Osb allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgap6 Mutation:  36 strains or lines available
References
Original:  J:258200 Lee GH, et al., A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO. J Cell Biol. 2016 Dec 5;215(5):705-718
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory