Ccdc141tm1.1Ygi
Targeted Allele Detail
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Symbol: |
Ccdc141tm1.1Ygi |
Name: |
coiled-coil domain containing 141; targeted mutation 1.1, Shigeru Yanagi |
MGI ID: |
MGI:6148229 |
Synonyms: |
CAMDI-KO |
Gene: |
Ccdc141 Location: Chr2:76840246-77000980 bp, - strand Genetic Position: Chr2, 45.38 cM, cytoband D
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Alliance: |
Ccdc141tm1.1Ygi page
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Germline Transmission: |
Earliest citation of germline transmission:
J:238090
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: Cre-mediated recombination of loxP sites surrounding exon 4 resulted in a null mutation. An frt-flanked neomycin selection cassette was inserted in intron 3. Western blot analysis of E16 mouse brain lysate demonstrated an absence of the encoded protein in homozygous mice.
(J:238090)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ccdc141 Mutation: |
81 strains or lines available
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Original: |
J:238090 Fukuda T, et al., Rescue of CAMDI deletion-induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor. EMBO Rep. 2016 Dec;17(12):1785-1798 |
All: |
2 reference(s) |
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