Tfr2^{em1(IMPC)Rbrc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tfr2^{em1(IMPC)Rbrc}
• Name: transferrin receptor 2; endonuclease-mediated mutation 1, RIKEN BioResource Center
• MGI ID: MGI:6148325
• Synonyms: Tfr2^em1Rbrc
• Gene: Tfr2 Location: Chr5:137568102-137585743 bp, + strand Genetic Position: Chr5, 76.57 cM
• Alliance: Tfr2^{em1(IMPC)Rbrc} page
• IMPC: Tfr2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele from IMPC was generated at RIKEN BioResource Center by injecting D10A RNA and 2 guide sequences CCGTGTTGGTGGTCGATGAAGAT, CCGGCCGGACCACGTTGTACTGG, which resulted in a Indel. (J:237616)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfr2 Mutation: 32 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)