Vgll3^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vgll3^em1(IMPC)H
• Name: vestigial like family member 3; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6149156
• Synonyms: Vgll3^-
• Gene: Vgll3 Location: Chr16:65612143-65663254 bp, + strand Genetic Position: Chr16, 37.34 cM, cytoband C1.3
• Alliance: Vgll3^em1(IMPC)H page
• IMPC: Vgll3 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology was used to induce a deletion of 890 nucleotides from the Vgll3 gene (including the functionally critical exon 2), resulting in a premature stop codon and a null allele. (J:237616, J:277773)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Vgll3 Mutation: 23 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 5 reference(s)