Phldb2^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phldb2^em1(IMPC)H
• Name: pleckstrin homology like domain, family B, member 2; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6149207
• Gene: Phldb2 Location: Chr16:45566606-45773961 bp, - strand Genetic Position: Chr16, 30.08 cM
• Alliance: Phldb2^em1(IMPC)H page
• IMPC: Phldb2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 2 guide sequences TCTCTTGGCAGACACCGGTTGGG, GGAGCCAGAATAGTCCCCGTTGG, which resulted in a Indel. (J:237616)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Phldb2 Mutation: 66 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)