Cyth1^tm1Jya
Targeted Allele Detail

Summary

• Symbol: Cyth1^tm1Jya
• Name: cytohesin 1; targeted mutation 1, Junji Yamauchi
• MGI ID: MGI:6149489
• Synonyms: cytohesin-1^-
• Gene: Cyth1 Location: Chr11:118054996-118139452 bp, - strand Genetic Position: Chr11, 82.96 cM, cytoband E2
• Alliance: Cyth1^tm1Jya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259473
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced exons 4 to 7. Western blot analysis confirmed absence of protein in sciatic nerve extracts. (J:259473)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyth1 Mutation: 74 strains or lines available

References

• Original: J:259473 Yamauchi J, et al., Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Sci Signal. 2012 Sep 25;5(243):ra69
• All: 1 reference(s)