Golgb1^m1Lanyu
Chemically induced Allele Detail

Summary

• Symbol: Golgb1^m1Lanyu
• Name: golgin B1; mutation 1, Yu Lan
• MGI ID: MGI:6149903
• Synonyms: ENU1483, Golgb1^ivs9+1-1A
• Gene: Golgb1 Location: Chr16:36695502-36753447 bp, + strand Genetic Position: Chr16, 26.19 cM, cytoband B4
• Alliance: Golgb1^m1Lanyu page

Mutation origin

• Strain of Origin: A/J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G-to-A transition at the intron-9 splice donor site. RT-PCR analysis showed that an aberrantly spliced transcript is expressed and western blot analysis showed that no detectable protein is expressed in homozygous mice. (J:235669)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Golgb1 Mutation: 117 strains or lines available

References

• Original: J:235669 Lan Y, et al., Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development. 2016 Jul 1;143(13):2344-55
• All: 1 reference(s)