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Golgb1em33Lanyu
Endonuclease-mediated Allele Detail
Summary
Symbol: Golgb1em33Lanyu
Name: golgin B1; endonuclease-mediated mutation 33, Yu Lan
MGI ID: MGI:6149904
Synonyms: Golgb1E13-41bp
Gene: Golgb1  Location: Chr16:36695502-36753447 bp, + strand  Genetic Position: Chr16, 26.19 cM, cytoband B4
Alliance: Golgb1em33Lanyu page
Mutation
origin
Strain of Origin:  FVB/NJ
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn indel mutation at exon 13 resulted in the deletion of 41 base pairs. Immunofluorescence staining of E13.5 homozygous embryos confirmed the absence of the Golgb1 protein in these mutants. (J:235669)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Golgb1 Mutation:  117 strains or lines available
References
Original:  J:235669 Lan Y, et al., Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development. 2016 Jul 1;143(13):2344-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory