Golgb1^em8Lanyu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Golgb1^em8Lanyu
• Name: golgin B1; endonuclease-mediated mutation 8, Yu Lan
• MGI ID: MGI:6149910
• Synonyms: Golgb1^E13-25bp
• Gene: Golgb1 Location: Chr16:36695502-36753447 bp, + strand Genetic Position: Chr16, 26.19 cM, cytoband B4
• Alliance: Golgb1^em8Lanyu page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A deletion mutation at exon 13 resulted in the deletion of 25 base pairs. The mutation causes a frameshift and introduces a premature stop codon. (J:235669)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Golgb1 Mutation: 117 strains or lines available

References

• Original: J:235669 Lan Y, et al., Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development. 2016 Jul 1;143(13):2344-55
• All: 2 reference(s)