Golga5^em2Lanyu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Golga5^em2Lanyu
• Name: golgin A5; endonuclease-mediated mutation 2, Yu Lan
• MGI ID: MGI:6149915
• Synonyms: Golga5^E4-13bp
• Gene: Golga5 Location: Chr12:102435394-102464166 bp, + strand Genetic Position: Chr12, 51.51 cM, cytoband F1
• Alliance: Golga5^em2Lanyu page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR mutagenesis introduced 13bp deletion in exon 4, resulting in a frame-shift and premature stop codon. Western blot analysis of tissue lysates from embryos showed that the encoded protein is absent in the homozygous mutant samples. (J:242905)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Golga5 Mutation: 39 strains or lines available

References

• Original: J:242905 McGee LJ, et al., Golga5 is dispensable for mouse embryonic development and postnatal survival. Genesis. 2017 Jul;55(7)
• All: 1 reference(s)