Rbm24^tm1.1Xch
Targeted Allele Detail

Summary

• Symbol: Rbm24^tm1.1Xch
• Name: RNA binding motif protein 24; targeted mutation 1.1, Xinbin Chen
• MGI ID: MGI:6149956
• Gene: Rbm24 Location: Chr13:46571910-46584571 bp, + strand Genetic Position: Chr13, 23.61 cM
• Alliance: Rbm24^tm1.1Xch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259290
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted 5' to exon 1 and a PGK_neomycin selection cassette followed by a second loxP site was inserted 3' to exon 2. Cre-mediated recombination removed exons 1 and 2 and the neomycin selection cassette. (J:259290)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Rbm24^tm1.1Xch

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm24 Mutation: 15 strains or lines available

References

• Original: J:259290 Zhang M, et al., Rbm24, a target of p53, is necessary for proper expression of p53 and heart development. Cell Death Differ. 2018 Jun;25(6):1118-1130
• All: 2 reference(s)