Tg(Mnx1-Zfp106,-EGFP)2Blk
Transgene Detail

Summary

• Symbol: Tg(Mnx1-Zfp106,-EGFP)2Blk
• Name: transgene insertion 2, Brian L Black
• MGI ID: MGI:6150003
• Transgene: Tg(Mnx1-Zfp106,-EGFP)2Blk Location: unknown
• Alliance: Tg(Mnx1-Zfp106,-EGFP)2Blk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Mnx1-Zfp106,-EGFP)2Blk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Zfp106 (MGI:1270153)

• Mutation details: The transgene comprises the following elements: the murine Mnx1 promoter, the murine Zfp106 gene with three N-terminal FLAG tags and two N-terminal STREP tags, an IRES and the EGFP fluorescent reporter gene. The promoter directs expression specifically in motor neurons. (J:241305)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:241305 Celona B, et al., Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 2017 Jan 10;6:e19032
• All: 1 reference(s)