Fem1a^tm1Seno
Targeted Allele Detail

Summary

• Symbol: Fem1a^tm1Seno
• Name: fem 1 homolog a; targeted mutation 1, Hiroshi Seno
• MGI ID: MGI:6150325
• Synonyms: EPRAP-deficient
• Gene: Fem1a Location: Chr17:56563810-56570610 bp, + strand Genetic Position: Chr17, 29.24 cM
• Alliance: Fem1a^tm1Seno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228893
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site flanked neomycin resistance gene cassette (Pr-Neo-pA) replaced the entire single-exon coding sequence of the gene. (J:228893)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fem1a Mutation: 13 strains or lines available

References

• Original: J:228893 Nakatsuji M, et al., EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis. PLoS Genet. 2015 Oct;11(10):e1005542
• All: 6 reference(s)