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Cipctm1.1Nju
Targeted Allele Detail
Summary
Symbol: Cipctm1.1Nju
Name: CLOCK interacting protein, circadian; targeted mutation 1.1, Model Animal Research Center of Nanjing University
MGI ID: MGI:6151055
Gene: Cipc  Location: Chr12:86993817-87012136 bp, + strand  Genetic Position: Chr12, 41.13 cM
Alliance: Cipctm1.1Nju page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:244550
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of the 3' UTR of exon 4. Cre-mediated recombination removed exon 3 and 4. QRT-PCR confirmed the absence of transcript expression in the liver regardless of circadian oscillation. (J:244550)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cipc Mutation:  19 strains or lines available
References
Original:  J:244550 Qu Z, et al., Inactivation of Cipc alters the expression of Per1 but not circadian rhythms in mice. Sci China Life Sci. 2015 Apr;58(4):368-72
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory