Slfn8^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Slfn8^tm1Aki
• Name: schlafen 8; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:6151479
• Synonyms: Slfn8^-
• Gene: Slfn8 Location: Chr11:82892984-82911636 bp, - strand Genetic Position: Chr11, 50.3 cM
• Alliance: Slfn8^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258797
• Parent Cell Line: GSI-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment encompassing the coding region was replaced with a neomycin-resistance gene cassette. (J:258797)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slfn8 Mutation: 52 strains or lines available

References

• Original: J:258797 Nakagawa K, et al., Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis. Int Immunol. 2018 Mar 8;30(2):69-78
• All: 1 reference(s)