About   Help   FAQ
Sp9tm1.2Zyan
Targeted Allele Detail
Summary
Symbol: Sp9tm1.2Zyan
Name: trans-acting transcription factor 9; targeted mutation 1.2, Zhengang Yang
MGI ID: MGI:6152405
Synonyms: Sp9flox
Gene: Sp9  Location: Chr2:73094809-73106115 bp, + strand  Genetic Position: Chr2, 43.52 cM
Alliance: Sp9tm1.2Zyan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:238868
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a FRT site followed by an splice acceptor (SA) fused to the internal ribosomal entry site (IRES) and a lacZ gene, a loxP site, a neomycin resistance gene cassette, a second FRT site and a second loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) intron 1 and a third loxP site immediately downstream of the exon2. Flpe-mediated recombination removed reporter and neo cassette from Sp9tm1Zyan leaving a single FRT site in intoron 1 and loxP flanked exon 2. This allele is a conditional-ready allele. (J:238868)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sp9 Mutation:  21 strains or lines available
References
Original:  J:238868 Zhang Q, et al., The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory