Nucb1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nucb1^em1(IMPC)Mbp
• Name: nucleobindin 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6152526
• Gene: Nucb1 Location: Chr7:45142300-45159813 bp, - strand Genetic Position: Chr7, 29.33 cM
• Alliance: Nucb1^em1(IMPC)Mbp page
• IMPC: Nucb1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at UC Davis by injecting CAS9 Protein and 4 guide sequences CCGGCGTCTAAAGTCATCTTTGG, CCTCTTTCAAATCAGTTCGTTCG, CCGGTACTGACTGGGAGCGCTCA, TCCCCCAATAAACAAAAAGGCGG, which resulted in a Exon Deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nucb1 Mutation: 24 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 5 reference(s)